Blood glucose levels within 7 days after birth in preterm infants according to gestational age.
10.6065/apem.2015.20.4.213
- Author:
Ju Young YOON
1
;
Hye Rim CHUNG
;
Chang Won CHOI
;
Sei Won YANG
;
Beyong Il KIM
;
Choong Ho SHIN
Author Information
1. Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Blood glucose level;
Preterm;
Birth weight;
Gestational age
- MeSH:
Apgar Score;
Birth Weight;
Blood Glucose*;
Body Weight;
Gestational Age*;
Glucose;
Humans;
Hyperglycemia;
Hypoglycemia;
Infant;
Infant, Newborn;
Infant, Premature*;
Parturition*;
Risk Factors
- From:Annals of Pediatric Endocrinology & Metabolism
2015;20(4):213-219
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: This study investigated blood glucose levels in preterm babies according to gestational age (GA). METHODS: Subjects were 141 preterm infants with a GA<34 weeks. Data on blood glucose levels, GA, body weight, glucose infusion rate, and other contributing factors in the first 7 days after birth were analyzed. Hypoglycemia was defined as a blood glucose level of <40 mg/dL up to 24 hours after birth and as <50 mg/dL thereafter. Hyperglycemia was defined as a blood glucose level >180 mg/dL. RESULTS: During the 7 days after birth, hypo- and hyperglycemia occurred in 29 (29 of 141, 20.6%) and 42 (42 of 141, 29.8%) neonates, respectively. During the first 2 hours, 18 neonates (12.8%) exhibited hypoglycemia, and only 2 (2 of 141, 1.4%) developed hyperglycemia. From 6 to 24 hours, hypo- and hyperglycemia were observed in 0 and 9 (9 of 141, 6.4%) neonates, respectively. Infants small for their GA (SGA) were at risk for hypoglycemia both within 24 hours (odds ratio [OR], 2.718; P=0.045) and during days 2 to 7 (OR, 4.454; P=0.006), and hyperglycemia during days 2 to 7 (OR, 3.200; P=0.005). Low 1-minite Apgar score was risk factor for both hypo- and hyperglycemia during days 2 to 7 (OR, 0.756; P=0.035 for hypoglycemia and OR, 0.789; P=0.016 for hyperglycemia). Both hypo- and hyperglycemia within 24 hours were less common in those who started feeding (OR, 0.294; P=0.013 for hypoglycemia and OR, 0.162; P=0.011 for hyperglycemia). CONCLUSION: Careful blood glucose level monitoring is required in preterm infants, especially SGA infants or those with low Apgar score. Early feeding could be beneficial for maintaining euglycemia.
