Second-day Sequential Organ Failure Assessment (SOFA) score as predictor in 30–day hospital mortality among Filipino adult patients who presented with Sepsis at the Emergency Department
- Author:
Christoper John N. Tibayan
1
;
Ferdinand G. Alcala
2
Author Information
- Publication Type:Journal Article
- Keywords: Sequential organ failure assessment; SOFA
- MeSH: Sepsis; Mortality; Philippines
- From: Philippine Journal of Internal Medicine 2019;57(3):127-132
- CountryPhilippines
- Language:English
-
Abstract:
Introduction:The Third International Consensus Definitions for Sepsis and Septic Shock in 2016 promoted the new definition and prognostication scheme among patients with sepsis using the Sequential Organ Failure Assessment (SOFA) scoring system. This study determined the discriminative power of the second-day SOFA scoring system in predicting 30-day hospital mortality among adult Filipino patients who presented with sepsis in a tertiary government hospital in the urban setting in the Philippines.
Methods:We evaluated 107 adult with sepsis presenting at the emergency department from June 1, 2017 to August 31, 2017 in a 300 bed capacity tertiary hospital. Receiving operating characteristic curves were generated to determine optimal cut off scores of the SOFA scoring system in predicting 30-day mortality. Binary logistic regression was performed to determine the association of the SOFA derivatives with hospital mortality. STATA 15 was used for data analysis.
Results:Second-day SOFA scores had excellent predictive ability for 30-day mortality at a cutoff point of 5, with sensitivity and specificity at 84.21% and 84.81%, respectively as compared with other SOFA derivatives at a given point in time.
Conclusion:The utility of second-day SOFA Score at a lower cut off score of five, has s a good discriminative power in predicting the all cause mortality among adult septic patients. This lower cut off score indicated a lower threshold trigger in identifying patients needing more intensive monitoring given the association of higher mortality risk in comparison with other studies done abroad. - Full text:Second_day_Sequential.pdf
