Complete excision of a rare case of Subependymal Giant Cell Astrocytoma (SEGA) in Tuberous Sclerosis Complex
- Author:
Norman D. Pagar
1
;
Maria Anna De Guzman
1
;
Criscely L. Go
1
Author Information
- Publication Type:Case Reports
- Keywords: Filipino; Endoport-assisted excision
- MeSH: Astrocytoma; Tuberous Sclerosis; Adult; Case report
- From: Philippine Journal of Internal Medicine 2021;59(1):32-36
- CountryPhilippines
- Language:English
- Abstract: Subependymal giant cell astrocytoma is a rare tumor that occurs in the walls of the lateral ventricles, foramen of Monro, and less frequently, in the third ventricle. It is one of the intracranial lesions found in tuberous sclerosis complex (TSC) ─ a rare multisystem genetic disease. We present a rare case of an adult Filipino with cutaneous signs of TSC, who initially presented with signs of increased intracranial pressure. The patient underwent right frontal craniotomy, endoport-assisted excision of the tumor with insertion of a ventriculoperitoneal (VP) shunt. Histopathology was consistent with a subependymal giant-cell astrocytoma WHO grade 1. The general status of the patient improved thereafter – there was the relief of headache and improvement in vision and gross hearing. Subependymal giant cell astrocytoma is a rare tumor of the central nervous system especially in adults, whose diagnosis is based on clinical, radiological, and histological, and immunohistochemical stains. It should be included in the differential diagnosis of a mass near the foramen of Monro. Given the hereditary nature of the disease, genetic counseling is essential when encountering patients with this condition.
- Full text:8 2020-068 Final Version.pdf
