Mechanism of lipid metabolism mediated by hepatokines and adipokines in nonalcoholic fatty liver disease
10.3969/j.issn.1001-5256.2023.01.026
- VernacularTitle:肝因子和脂肪因子介导的脂代谢在非酒精性脂肪性肝病中的作用机制
- Author:
Chenlu ZHAO
1
;
Dongfang SHANG
1
;
Cheng ZHOU
1
;
Junhao SHI
1
;
Wenxia ZHAO
2
Author Information
1. The First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou 450000, China
2. Department of Hepatology and Spleen-Stomach, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000, China
- Publication Type:Review
- Keywords:
Non-alcoholic Fatty Liver Disease;
Hepatokines;
Adipokines
- From:
Journal of Clinical Hepatology
2023;39(1):168-174
- CountryChina
- Language:Chinese
-
Abstract:
Nonalcoholic fatty liver disease (NAFLD) has been renamed as metabolic-associated fatty liver disease, and systemic metabolic dysfunction has become one of the concerns of this disease. NAFLD is a metabolic disease based on dyslipidemia in the liver, which is closely associated with adipose tissue. Hepatokines and adipokines secreted by the liver and adipose tissue play an important role in regulating liver lipid metabolism. This article summarizes the hepatokines and adipokines that can promote or inhibit lipid metabolism, focusing on the mechanism of lipid metabolism mediated by hepatokines and adipokines in NAFLD, so as to provides ideas and a theoretical basis for clinical prevention and treatment.
