Level of Plasma Stromal Derived Factor-1 in Essential Hypertension Patient and Effect of Enalapril on It
- VernacularTitle:原发性高血压患者血浆基质细胞衍生因子-1水平变化及依那普利的影响
- Author:
Xiang LI
;
Yan YAN
;
Nan LI
- Publication Type:Journal Article
- Keywords:
essential hypertension, stromal cell-derived factor 1, angiotensin-converting enzyme inhibitor, Enalapril
- From:
Chinese Journal of Rehabilitation Theory and Practice
2010;16(5):419-420
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the level of plasma stromal cell-derived factor-1 (SDF-1) in essential hypertension and the effect of angiotensin-converting enzyme inhibitor Enalapril on it. MethodsThe levels of plasma SDF-1 in 34 patients with hypertension and 28 normal healthy people were detected with ELISA. Hypertension patients were detected again after 2-week Enalapril treatment. ResultsThe level of SDF-1 in hypertension patients was （4.211±1.132） mmol/L, higher than control (3.568±0.936) mmol/L （P<0.05）, and became （4.950±1.050） mmol/L after treatment, higher than pre-treatment （P<0.05）. ConclusionThe level of SDF-1 increases in patients with hypertension, and Enalapril can further increase the level.
