Steroid and enalapril therapy: possible cause of toxic epidermal necrolysis.
10.3345/kjp.2006.49.3.332
- Author:
Dong Wook KIM
1
;
Da Eun JUNG
;
Ja Wook KOO
Author Information
1. Department of Pediatrics, Sanggye Paik Hospital, Inje University, College of Medicine, Seoul, Korea. koojw9@sanggyepaik.ac.kr
- Publication Type:Case Report
- Keywords:
Steroid;
Enalapril;
Toxic epidermal necrolysis;
Intravenous immunoglobulin
- MeSH:
Enalapril*;
Epidermis;
Glomerulonephritis, Membranous;
Immunization, Passive;
Mucous Membrane;
Necrosis;
Steroids;
Stevens-Johnson Syndrome*
- From:Korean Journal of Pediatrics
2006;49(3):332-336
- CountryRepublic of Korea
- Language:English
-
Abstract:
Toxic epidermal necrolysis (TEN) is a rare, acute and life-threatening cutaneous drug reaction. TEN is characterized by the sudden onset of extensive necrosis in the epidermis and frequent mucous membrane involvement. The pathogenesis has not yet been elucidated. In addition, no particular treatment for TEN has been established. We report a case of TEN in a 14-year-old-boy, which might have been caused by steroids with enalapril treatment for membranous nephropathy. He recovered after intravenous immunoglobulin therapy.
