Gastrointestinal manifestations of COVID-19: An updated systematic review
https://doi.org/10.47665/tb.39.3.013
- Author:
Alzahrani, O.R.
1
,
2
;
Alanazi, A.D.
3
;
Hawsawi, Y.M.
4
,
5
;
Alatwi, H.E.
1
,
2
;
Alharbi, A.A.
2
,
6
Author Information
1. Department of Biology, Faculty of Science, University of Tabuk, Tabuk, Kingdom of Saudi Arabia&
2. Genome and Biotechnology Unit, Faculty of Science, University of Tabuk, Tabuk, Kingdom of Saudi&
3. Department of Biological Sciences, Faculty of Science and Humanities, Shaqra University, P.O. Box 1040, Ad-Dawadimi 11911, Saudi Arabia
4. Research Center, King Faisal Specialist Hospital and Research Center, Jeddah 21499, P.O. Box 40047, MBC J-04, Kingdom of Saudi Arabia&
5. College of Medicine, Al-Faisal University, P.O. Box 50927, Riyadh, 11533, Saudi Arabia
6. Department of Biochemistry, Faculty of Sciences, University of Tabuk, Tabuk, Kingdom of Saudi Arabia
- Publication Type:Review
- Keywords:
Coronavirus;
gastrointestinal;
symptoms;
vomiting;
diarrhea
- From:Tropical Biomedicine
2022;39(No.3):428-433
- CountryMalaysia
- Language:English
-
Abstract:
Lack of knowledge about the type and prevalence of gastrointestinal symptoms as a clinical manifestation
is one of the reasons for delayed diagnosis and treatment of COVID-19 patients. This review study aimed
to systematically review the type and prevalence of gastrointestinal symptoms in COVID-19 patients.
To study the gastrointestinal manifestations of COVID-19, we used the 06- PRISMA registered in the
CAMARADES-NC3Rs Preclinical Systematic Review and Meta-Analysis Facility (SyRF) database. PubMed,
Embase, Web of Science, Google Scholar, and Scopus databases were searched for publications on the
gastrointestinal manifestations of COVID-19 with no publication time frame. Articles were found using
the following terms and search strategy: [“COVID-19, Coronavirus, 2019-nCoV, Clinical SymptomsGastrointestinal or gastric or intestinal manifestations”]. Out of 27652 papers, 35 papers on a total of
6730 COVID-19 patients up to 2022 met the inclusion criteria. Remarkably, most articles (28 papers,
77.8%) were from China (77.8%). The most common gastrointestinal manifestations were nausea or
vomiting (13.1%), diarrhea (11.05%), anorexia (8.7%), and abdominal pain (2.4%), respectively. The
findings of the present review revealed that contrary to what was initially assumed in the COVID-19
outbreak, this infection does not manifest only as respiratory symptoms but also as gastrointestinal
symptoms. Therefore, clinicians and gastroenterologists must be alert to these unusual cases and
fecal–oral transmission during the COVID-19 pandemic and implement preventive strategies.
- Full text:8.2022my1358.pdf
