PURPOSE: Cancer constitutes a public health concern and has been an evident universal health problem for the past decade. New treatment options with the goal of finding an absolute cure for the disease are explored by the medical society. This study aims to examine the Health-Related Quality of Life and levels of hope among patients with cancer undergoing adjuvant therapy, and to determine the relationship of these variables, their domains and subscales.

METHODS: The study used a descriptive, cross-sectional, correlational research design. Ninety two respondents from Porac, Pampanga, aged 18 and above, diagnosed with cancer, and are undergoing adjuvant therapy were selected via consecutive sampling. Two instruments were utilized in the study: the EORTC QLQ-C30 and the Herth Hope Index. Pearson's r with a p-value set at

FINDINGS: Results revealed that over a half of the respondents (53.26%) have high HRQoL scores (mean of 68.5) in the EORTC QLQ- C30 questionnaire. On the other hand, the overall level of hope based on the Herth Hope Index was 33.32, which was generally acceptable, where 66.30% of the scores were considered high. Domains of HRQoL namely physical functioning, role functioning, emotional functioning, cognitive functioning and social functioning were all positively correlated with hope subscales specifically:
temporality and future, readiness and expectancy and interconnectedness at varying strengths.

CONCLUSIONS: A diagnosis of cancer does not equate to one's loss of hope. Hope may be anchored in Health-Related Quality of Life which involves different domains rather than in the form of treatments for cure. Further studies which focus on comparing outcomes of
patients who decline and those who willingly undergo adjuvant therapy, a repeated measures study to determine continuum levels and lastly, an intervention study focusing on symptom management may be done to gain more in-depth information regarding the effects of adjuvant therapy on the HRQoLand level of hope among these patients.