BACKGROUND AND OBJECTIVE: Conventional red cell transfusion formulae used in clinical practice has shown underestimation of the actual post-transfusion hemoglobin level. To address this problem, we aimed to determine if there is an agreement between computed and actual post-transfusion hemoglobin levels using an alternative red cell transfusion formula.

METHODOLOGY: This was a prospective, cross-sectional study. Using Morris' formula, the red cell volume requirements of the participants were computed and post-transfusion hemoglobin levels were obtained for comparison.

RESULT: Majority of the 116participants belongs to age between 2 to 5 years (39.5%) and female (54.3%). Most common indication was hemoglobin level < 7 g/dL with manifestations of anemia (56%). The computed and actual post-transfusion hemoglobin were in agreement. The increase in hemoglobin had direct relationship to the volume of blood transfused and inverse relationship to the age and weight of the patients.

CONCLUSION: Using Morris' formula, the computed and actual post-transfusion hemoglobin values were in agreement. The volume of transfused red cells, age, and weight are predictors of the increase in post-transfusion hemoglobin. This formula can be adopted for Filipino pediatric patients and can obviate the need for hemoglobin determination after transfusion.