Prenatal Diagnosis of Fetal Goiter in a Euthyroid Mother.
10.14734/kjp.2015.26.4.365
- Author:
Jin Young BAE
1
;
Lee Hyun JOO
;
Ji Eun JUNG
;
Seong Yeon HONG
Author Information
1. Department of Obstetrics and Gynecology, School of Medicine, Catholic University of Daegu, Korea. magu815@cu.ac.kr
- Publication Type:Case Report
- Keywords:
Congenital hypothyroidism;
Goiter;
Prenatal diagnosis
- MeSH:
Adult;
Amniocentesis;
Cesarean Section;
Congenital Hypothyroidism;
Cordocentesis;
Female;
Goiter*;
Humans;
Hypothyroidism;
Infant, Newborn;
Mothers*;
Pathology;
Pregnancy;
Prenatal Diagnosis*;
Thyroid Function Tests;
Thyroid Gland;
Thyroxine
- From:Korean Journal of Perinatology
2015;26(4):365-368
- CountryRepublic of Korea
- Language:English
-
Abstract:
Congenital fetal goiter is a very rare pathology, is sometimes difficult to diagnose when there is no maternal history or the goiter size is moderate. We report a case of prenatally diagnosed fetal goiter in a euthyroid mother. A 28-year-old woman was referred to our clinic at 38(+2) weeks of gestation. Ultrasonographic examination revealed a fetal goiter. The maternal history and thyroid function tests, including antithyroid autoantibody tests, were unremarkable. Cesarean section was performed, and the thyroid profile of the neonate was consistent with congenital hypothyroidism. Thyroxine therapy was immediately started. Fetal thyroid function must be determined when a goiter is detected. Cordocentesis is a more reliable but riskier diagnostic tool than amniocentesis. Intra-amniotic injection of thyroxine is relatively safe and an easier management option for fetal hypothyroidism. To develop more noninvasive and safe methods for therapeutic efficacy monitoring, a large-scale study is necessary.
