Investigation of inhibitory effect on growing malignant tumors of the flavonoid preparation from leaves of TanCuong tea (ThaiNguyen province)
- Author:
Binh Thi Thanh Ha
- Publication Type:Journal Article
- Keywords:
cancer
- MeSH:
neoplasms;
Flavonoids
- From:Pharmaceutical Journal
2002;316(8):23-30
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
A flavonoid preparation was extracted from TanCuong tea leaves and was studied on the cultured cancer cells and on the thigh tumor in mice. Flavonoids from T©n C¬ng tea leaves (FTC) exhibited anticarcinogenic activity in vitro. FTC inhibited the reproduction of Hep-2 (human' carcinoma cell); Sp-2/O (cancer cells from mouse bone marrow) and S180 (Sarcoma cell). The most activity is on S180. In vivo, the experiments have been done in white mice BA/bc showed that FTC inhibited tumor promotion in mice. In addition, FTC decreased the metastasis of S180 into liver and lung of mice.