Intradural extramedullary tumor causing compression of the thoracic and lumbar vertebrae in a 22-year-old male with Acute Myeloid Leukemia.
https://doi.org/10.47895/amp.v54i2.1528
- Author:
Ronna Cheska V. DE LEON
1
;
Camille Ariadne C. TANCHANCO
2
;
Ma. Angelina L. MIRASOL
2
;
Joven Jeremius Q. TANCHUCO
3
Author Information
1. Department of Medicine, Philippine General Hospital, University of the Philippines Manila
2. Section of Hematology, Department of Medicine, College of Medicine and Philippine General Hospital, University of the Philippines Manila
3. Section of Pulmonology, Department of Medicine, College of Medicine and Philippine General Hospital, University of the Philippines Manila
- Publication Type:Journal Article
- Keywords:
Intradural Tumor;
T (8;
21) Translocations;
Acute Myeloid Leukemia
- MeSH:
Human;
Leukemia, Monocytic, Acute;
Sarcoma, Myeloid;
Spinal Cord Neoplasms
- From:
Acta Medica Philippina
2020;54(2):210-215
- CountryPhilippines
- Language:English
-
Abstract:
Myeloid sarcoma, characterized by the presence of immature myeloid cells occurring at an extramedullary site, is a rare manifestation of acute myelogenous leukemia (AML). Spinal cord compression as an initial presentation of AML is very rare with only a few reported cases. We discuss a case of a 22-year-old male who presented with bicytopenia and paraplegia. Workups were consistent with AML with monocytic differentiation. Chromosomal analysis revealed loss of Y and t (8;21). Spinal cord MRI showed intradural extramedullary-enhancing soft tissue lesions at levels T2 to T7 and L5 to S1, suspected to be myeloid sarcoma. Patient, however, succumbed to severe nosocomial infection prior to initiation of chemotherapy and radiotherapy.
- Full text:1528-Article Text-7006-1-10-20200430.pdf
