Systemic lupus erythematosus with coexistent psoriasis vulgaris: A case report.

Author: Joyce Ann S TAN ¹ ; Erin Jane L TABABA ² ; Coralie D DIMACALI ³ ; Claudine YAP-SILVA ²
Author Information

1. Section of Dermatology, Department of Medicine, Philippine General Hospital, University of the Philippines Manila
2. Section of Dermatology, Department of Medicine, College of Medicine and Philippine General Hospital, University of the Philippines Manila
3. Section of Nephrology, Department of Medicine, College of Medicine and Philippine General Hospital, University of the Philippines Manila Manila
Publication Type:Journal Article
MeSH: Human; Female; Adult; Hydroxychloroquine; Glucocorticoids; Methotrexate; Biological Products; Lupus Erythematosus, Systemic; Psoriasis; Precipitating Factors; Disease Susceptibility
From: Acta Medica Philippina 2017;51(4):347-350
CountryPhilippines
Language:English
Abstract:
We report a 42-year-old female with a 20-year history of systemic lupus erythematosus who subsequently developed psoriasis vulgaris. She has been on chronic, erratic prednisone and hydroxychloroquine intake prior to appearance of psoriatic lesions. Hydroxychloroquine and glucocorticoids are possible triggers of this phenomenon. Both diseases have a shared susceptibility loci and a shared Th17 pathophysiologic pathway.Treatment with methotrexate and selected biologics can target both disease mechanisms.
Full text:520-Article Text-1996-1-10-20191121.pdf