Effects of Electroacupuncture on IL-1β after Total Cerebral Ischemia-reperfusion in Rats
- VernacularTitle:电针对全脑缺血-再灌注大鼠IL-1β的影响
- Author:
Zejun HUO
;
Zhigang LI
;
Jia GUO
;
Zhaoxing TIAN
- Publication Type:Journal Article
- Keywords:
cerebral ischemia-reperfusion, electroacupuncture, interleukin-1β
- From:
Chinese Journal of Rehabilitation Theory and Practice
2010;16(4):342-343
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the effects of electroacupuncture on IL-1β in brain tissue of rats after total cerebral ischemia-reperfusion.MethodsThirty male Wistar rats were randomly divided into the sham operation group, model group and acupuncture group, in each group. In acupuncture group and model group, 4-vessel-occlusion method was used to make a rat model of cerebral ischemia reperfusion. Acupuncture group used electroacupuncture on points Quchi and Zusanli, 6 hours after reperfusion. The rats of each group were killed and ELISA was used for the measurement of IL-1β in brain tissues.ResultsIL-1β in brain tissue in model group increased significantly compared with sham operation group and acupuncture group(P<0-001). No significant differences were found between sham operation group and acupuncture group (P>0-05).ConclusionAcupuncture can lower IL-1β content of brain tissue of rats with brain ischemia/reperfusion injury.
