Clinical features and prognostic factors in Korean patients hospitalized for coronary artery disease (Catholic Heart Care Network Study).
- Author:
Jin Man CHO
1
;
Chong Jin KIM
;
Woo Seung SHIN
;
Eun Ju CHO
;
Chul Soo PARK
;
Pum Joon KIM
;
Jong Min LEE
;
Sang Hyun IHM
;
Hyou Young RHIM
;
Kiyuk CHANG
;
Keon Woong MOON
;
Yong Ju KIM
;
Hae Ok JUNG
;
Hee Yeol KIM
;
Ji Won PARK
;
Seung Won JIN
;
Hui Kyung JEON
;
Yong Seog OH
;
Ki Dong YOO
;
Doo Soo JEON
;
Sang Hong BAEK
;
Gil Whan LEE
;
Ho Joong YOUN
;
Man Young LEE
;
Wook Sung CHUNG
;
Jun Chul PARK
;
Ki Bae SEUNG
;
Tai Ho RHO
;
Chul Min KIM
;
In Soo PARK
;
Jang Seong CHAE
;
Jae Hyung KIM
;
Kyu Bo CHOI
;
Soon Jo HONG
Author Information
1. Kyung Hee University College of Medicine, Seoul, Korea. chongjinkim0316@yahoo.co.kr
- Publication Type:Original Article
- Keywords:
Coronary disease;
Intervention;
Prognosis
- MeSH:
Acute Coronary Syndrome;
Coronary Artery Disease*;
Coronary Disease;
Coronary Vessels*;
Death;
Dyslipidemias;
Follow-Up Studies;
Heart*;
Hospitals, University;
Humans;
Hypertension;
Incidence;
Korea;
Mortality;
Myocardial Infarction;
Percutaneous Coronary Intervention;
Prognosis;
Prospective Studies;
Risk Factors;
Smoke;
Smoking;
Stents
- From:Korean Journal of Medicine
2007;73(2):142-150
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Coronary artery disease (CAD) has recently become one of the major causes of mortality and morbidity in Korea. However, not much epidemiologic and demographic data has yet been reported. The purpose of this study was to investigate the clinical features as well as the prognostic factors of patients with CAD. METHODS: We prospectively enrolled 1,665 consecutive patients with CAD who had been admitted to the Catholic University Hospitals from December 1999 to April 2003. RESULTS: Acute myocardial infarction (AMI) was the most common cause of admission (n=715, 42.9%). Dyslipidemia, hypertension and smoking were the most common risk factors. More than 70% of the patients who underwent percutaneous coronary intervention (PCI) received stent implantation. A total of 965 (612 males) patients were followed at least for 6 months (the mean follow-up duration was 23.8+/-12.2 months). The incidence rates of major adverse cardiac events (MACE: cardiac death, acute myocardial infarction, target vessel revascularization) and cardiac death were 15.1% (n=146) and 2.2% (n=21), respectively. There was no difference in overall survival between the patients treated with medical therapy and those treated with PCI. By Cox regression analysis, the independent prognostic factors for MACE were PCI (95% CI: 1.75-4.85; p<0.01) and multivessel disease (95% CI: 1.03-2.04; p<0.05), and the independent prognostic factors for cardiac death were medical therapy (95% CI: 1.08-14.41; p<0.05) and old age (95% CI: 1.13-16.13; p<0.05). CONCLUSIONS: There was no difference in overall survival between the patients treated with medical therapy and those treated with PCI. However, PCI was superior to medical therapy for preventing death of the patients with acute coronary syndrome.
