Advance in Neurogenesis after Focal Cerebral Ischemia-reperfusion Injury and Effect of Drug (review)
- VernacularTitle:局灶性脑缺血再灌注后神经发生及药物对其作用的研究进展
- Author:
Jie XIANG
;
Dongming XU
;
Wen WANG
;
Cailin YUN
;
Li ZHANG
;
Houxi AI
;
Lin LI
- Publication Type:Journal Article
- Keywords:
cerebral ischemia-reperfusion, neurogenesis, drug, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2010;16(2):103-105
- CountryChina
- Language:Chinese
-
Abstract:
Neural stem cells (NSCs), which will proliferate and differentiate into neurons and glial cells under certain conditions, involved in the repair of neurological function. This process is called neurogenesis. Focal cerebral ischemia-reperfusion injury is one of the most common diseases, which can induce the neurological functional deficits. It is significant to study the response and regulation of NSCs after focal cerebral ischemia-reperfusion injury. In this article, we reviewed the characteristics, molecular mechanisms, putative endogenous mediators and exogenous stimulators of neurogenesis in adult brain following ischemic injury, and response and regulation of drug in ischemic injury following neurogenesis.
