Situation and Related Factors of Maintenance Medication Treatment in Schizophrenic Patients Re-hospitalized for Relapse

VernacularTitle:再住院精神分裂症患者的药物维持治疗状况及影响因素
Author: Daguang ZHANG ; Xiaojing GU ; Lirong TANG ; Junhua GUO ; Jiuying WANG ; Xin MA ; Shuhua WU ; Lu CAI ; Weiming ZHAO ; Qing HUANG ; Yongzhen WONG ; Wenqiang ZHANG ; Yancun FENG ; Yingqiang XIANG
Publication Type:Journal Article
Keywords: schizophrenia, relapse, re-hospitalization, maintenance medication therapy
From: Chinese Journal of Rehabilitation Theory and Practice 2012;18(9):858-860
CountryChina
Language:Chinese
Abstract: Objective To survey the situation and related factors of maintenance medication treatment in schizophrenic patients re-hospitalized for relapse. Methods 362 patients re-admitted with schizophrenia and their relatives were interviewed with questionnaire which included 16 factors that might affect maintenance medication treatment. Results 63.8% patients stopped medication and 21.1% patients were on low-dose maintenance medication treatment by themselves, while 7.7% patients were on reasonable dose anti-psychotics in 2 years. The time of maintenance medication treatment related with insight (OR=2.2144, P=0.001), family care (OR=4.8842, P=0.025), outcomes of treatment (OR=2.2056, P=0.007) and negative life events (OR=0.4529, P=0.003). Conclusion Schizophrenic patients re-admitted with relapse often withdraw or reduce their medication by themselves, which risked with poor insight, poor therapeutic effect, poor care from their family, and more negative life events