Progress and prospect of heart transplantation in children
10.3969/j.issn.1674-7445.2023.01.007
- VernacularTitle:儿童心脏移植的治疗进展与展望
- Author:
Jiade ZHU
1
;
Min WU
Author Information
1. Department of Cardiac Surgery, Guangdong Cardiovascular Institute, Guangdong Academy of Medical Science, Guangdong Provincial People's Hospital, Guangzhou 510080, China
- Publication Type:Research Article
- Keywords:
Pediatric heart transplantation;
Refractory heart failure;
Congenital heart disease;
Ventricular assist device;
ABO-incompatibility;
Weight mismatch;
Heart allocation;
Bridge to transplant (BTT)
- From:
Organ Transplantation
2023;14(1):56-
- CountryChina
- Language:Chinese
-
Abstract:
Pediatric heart transplantation is the standard treatment for children complicated with refractory heart failure which is difficult to be treated by conventional surgery or drugs. At present, an increasing quantity of pediatric heart transplantation is being performed worldwide, whereas relevant experience is still lacking in China. In recent 10 years, significant progress has been achieved in pediatric heart transplantation. On one hand, the number of pediatric heart transplantation has been increased year by year. On the other hand, ABO-incompatible heart transplantation, application of ventricular assist device in children, and recipient-donor weight mismatch transplantation have been widely employed to resolve the shortage of donor heart in pediatric heart transplantation. However, relevant experience of pediatric heart transplantation is lacking in China, especially in understanding the indications of pediatric heart transplantation and the application of specific strategies for pediatric heart transplantation, etc. In this article, the development history, advances in therapeutic strategy and clinical prognosis of pediatric heart transplantation were reviewed.
