A Clinical Review of Solid and Papillary Epithelial Neoplasm of the Pancreas.
- Author:
Sung Heun KIM
1
Author Information
1. Department of Surgery, Dong-A University College of Medicine, Busan, Korea. heun007@hanmail.net
- Publication Type:Original Article
- Keywords:
Solid and papillary epithelial neoplasm;
Pancreas
- MeSH:
Abdominal Pain;
Academic Medical Centers;
Female;
Follow-Up Studies;
Head;
Humans;
Neoplasms, Glandular and Epithelial*;
Pancreas*;
Pancreatectomy;
Prognosis;
Recurrence;
Retrospective Studies;
Ultrasonography
- From:Korean Journal of Hepato-Biliary-Pancreatic Surgery
2003;7(1):139-143
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Solid and papillary epithelial neoplasm (SPEN) of the pancreas is a rare malignant tumor with a characteristic female predominance. This tumor has a low- grade malignant potential biologically, and shows favorable prognosis with surgical treatment clinically. METHODS: Nine patients with SPEN of the pancreas who were pathologically confirmed at the Dong-A University Medical Center were analyzed retrospectively. Clinical data, including clinical manifestation, diagnostic maneuvers, surgical treatment modality, and prognosis were evaluated. RESULTS: Six out of nine patients were females with a mean age of 28 (range, 15~52) years. Except in 2 cases, all patients presented with either a palpable abdominal mass (5 cases) or abdominal pain (2 cases). The tumors ranged in size from 3.8 to 18 (average size, 11.4) cm. Five were located in the body, 3 in the tail, and 1 in the head. SPEN was diagnosed preoperatively in 6 patients by abdominal ultrasonography and/or CT. All patients underwent surgical resection, which included subtotal pancreatectomies (4 cases), distal pancreatectomies (4 cases, 1 by laparoscopically) and local excision (1 case). All patiests are survived without evidence of recurrence with a mean follow up of 53.1 (range, 26~69) months. CONCLUSION: SPEN of the pancreas is low-malignant in character, and complete surgical excision is the treatment of choice which warrants a long-term survival.
