Relationship between N-terminal-pro-B-type Natriuretic Peptide and Left Ventricular Mass Index in Elderly Hypertension Patients
- VernacularTitle:老年高血压患者不同心室构型与氮末端B型脑钠肽前体的相关性
- Author:
Peng GAO
;
Qiwei ZHU
;
Ruixue DU
;
Leiming LUO
- Publication Type:Journal Article
- Keywords:
hypertension, elderly, left ventricular mass index, N-terminal-pro-B-type natriuretic peptide
- From:
Chinese Journal of Rehabilitation Theory and Practice
2011;17(5):454-456
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the N-terminal-pro-B-type natriuretic peptide (NT-proBNP) concentration in the difference myocardial wall motion after essential hypertension. Methods 326 patients with essential hypertension and normal heart function and 265 control subjects were measured with their NT-proBNP. According to Canau's categories, the ventricle geometries of patients with high left ventricular mass index were divided into 2 groups. Results NT-proBNP was significantly higher in patients with hypertension than in controls. After grouped by different myocardial wall motion, the patients with concentric hypertrophy were highest among all the groups; the groups with eccentric hypertrophy was secondly highest; concentric remodeling and normal geometric pattern were not significantly higher than the controls. Conclusion NT-proBNP is different in patients with different myocardial wall motion before heart failure, which may play an important role in myocardial remodeling.