Progress of relationship between Helicobacter pylori infection and colorectal cancer
10.3760/cma.j.cn115355-20200713-00382
- VernacularTitle:幽门螺杆菌感染与结直肠癌关系的研究进展
- Author:
Jiangtao LIANG
1
;
Chunbao ZHAI
Author Information
1. 山西医科大学研究生院,太原 030001
- Keywords:
Helicobacter pylori;
Colorectal neoplasms;
Risk factors
- From:
Cancer Research and Clinic
2022;34(11):866-869
- CountryChina
- Language:Chinese
-
Abstract:
Studies on the relationship between Helicobacter pylori infection and colorectal cancer have been controversial in recent years. The Chinese "eat-together system" dietary culture and the life style of family gathering result in a high infection rate of Helicobacter pylori, and the relationship between Helicobacter pylori and tumors has thereupon become one of the research hotspots. Studies have shown that Helicobacter pylori infection may promote the occurrence of colorectal precancerous lesions and colorectal cancer by inducing hypergastrinemia, destroying intestinal microecology, suppressing immune function and other ways. This article reviews the research progress on the relationship between Helicobacter pylori infection and colorectal cancer and its mechanism.