Clinical efficacy of injection of recombinant humanized type Ⅲ collagen in facial rejuvenation
10.3760/cma.j.issn.1671-0290.2022.04.012
- VernacularTitle:微针注射重组Ⅲ型人源化胶原蛋白对皮肤年轻化的效果
- Author:
Lideng CAO
1
;
He QIU
;
Shuo LIU
;
Hang WANG
Author Information
1. 四川大学华西口腔医院医疗美容科 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心，成都 610041
- Keywords:
Face;
Rejuvenation;
Collagen Type Ⅲ;
Recombinant humanized type Ⅲcollagen;
Microneedle injection
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2022;28(4):300-303
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the efficacy of recombinant humanized type Ⅲ collagen injected by microneedles in facial rejuvenation.Methods:Twenty-five cases recruited from July to December 2021 were included as the research objects in this study. Recombinant humanized type Ⅲ collagen was injected into the face skin using microneedles. Images were collected before the treatment and 1, 2, and 3 months after the end of the treatment. The VISIA image analysis system was used for comparative analysis. Patient′s satisfaction evaluation and the occurrence of complications after treatment were also recorded.Results:According to results of VISIA, the scores of spots were (32.06±6.92) and (27.59±7.69); red areas were (32.79±11.80) and (27.74±9.49); pores were (17.66±9.79) and (14.60±7.07) and brown spots were (43.61±11.93) and (37.59±16.22) after the treatment were lower than those before treatment, and the results were statistically different ( F=3.442, 4.209, 7.473, 7.113, P<0.05). One month after the end of the of treatment. Patient′s self-satisfaction reached 84% (21 cases); three months after the end of the treatment, the patient′s self-satisfaction reached 80% (20 cases). No serious adverse reactions were occurred. Conclusions:The recombinant humanized type Ⅲ collagen injected by microneedles can be effective and durable for facial rejuvenation and get high patient satisfaction. It has high safety and is worthy of clinical promotion.
