Effects of skin care products containing oligopeptides and bio-polysaccharides on sensitive skin barrier function
10.3760/cma.j.issn.1671-0290.2022.03.013
- VernacularTitle:含寡肽及生物多糖护肤品改善敏感性皮肤屏障功能的效果
- Author:
Meng WEI
1
;
Zhaoyan GAN
;
Ying WANG
;
Xiangyun LI
;
Hongkai LI
;
Xiumin YANG
Author Information
1. 首都医科大学附属北京同仁医院皮肤科，北京 100730
- Keywords:
Skin;
Sensitive skin;
Skin barrier;
Skin water content;
Trans epidermal water loss;
Oligopeptides;
Bio-polysaccharides
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2022;28(3):213-217
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effects and adverse reactions of external skin care products containing oltides and bio-polysaccharides on epidermaligopep barrier function of sensitive skin.Methods:From December 2019 to July 2020, there were 30 sensitive skin volunteers diagnosed and treated in the dermatology clinic of Beijing Tongren Hospital, including 3 males and 27 females, aged 18-57 years, with an average of 34 years, and the course of disease was 1-10 years, with an average of 5.75 years. They were treated once with products containing oligopeptides and biopolysaccharides on the day of enrollment. Before treatment, 1 week and 4 weeks after treatment, we observed and evaluated through VISIA analysis; skin physiological index measurement, subjective and objective improvement assessment, and product safety were evaluated through questionnaire surveys.Results:The VISIA data showed that the red zone was significantly lower than the baseline, and the data at the 4th week and before treatment were significantly improved ( P<0.05). On skin physiology, the test showed that after treatment, the difference between two follow-up visits and the water content before was statistically significant ( P<0.05). TEWL value after 4 weeks of treatment was significantly improved as compared with the baseline ( P<0.05). During the entire study process, no adverse reactions related to the product occurred. Conclusions:This skin care product containing oligopeptides and biopolysaccharides can increase the water content of the sensitive skin, reduce the water loss through the skin, and improve the skin barrier function. Meanwhile, no server adverse reaction is detected through the whole experiment.
