The clinical research process management indicator system based on the theory of Hazard Analysis and Critical Control Point
10.3760/cma.j.cn113565-20220329-00047
- VernacularTitle:基于HACCP构建临床研究项目全流程管理指标体系
- Author:
Miao MIAO
1
;
Lingling YU
;
Xin WANG
;
Haijuan ZHAO
;
Qingqing WANG
;
Fei LIU
;
Pengjun ZHANG
Author Information
1. 北京医院 国家老年医学中心 中国医学科学院老年医学研究院，北京 100730
- Keywords:
Hazard Analysis and Critical Control Point;
Clinical research process management;
Indicator system
- From:
Chinese Journal of Medical Science Research Management
2022;35(5):338-343
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To build an investigator-initiated clinical research process management indicator system based on the theory of Hazard Analysis and Critical Control Point(HACCP).Methods:A plan was developed according to HACCP principles, and 23 experts were invited to form an expert advisory group. Literature research, panel discussion, and Delphi method were used to collect clinical research process management indicators, and the weight of each indicator was calculated via Analytic Hierarchy Process(AHP).Results:Two rounds of expert consultation were carried out with a high positive coefficient and a high expert authority level, and finally formed 3 primary indicators and 14 secondary indicators. The primary indicators were project establishment, project process management, and project implementation assessment, with weights of 0.142 8, 0.714 4, and 0.142 8, respectively.Conclusions:This study established a clinical research process management system based on HACCP theory from 3 dimensions: project establishment, project process management, and project implementation assessment, carried out precise management of clinical research according to the weights of secondary indicators, focusing on the content of indicators with great weight, and provided an important reference for the management of investigator-initiated clinical research.
