A review of advances in intraocular fluid detection for high myopia and its relevant fundus diseases
10.3760/cma.j.cn511434-20211008-00565
- VernacularTitle:眼内液分子参与高度近视及其眼底病变发病机制的研究进展
- Author:
Jinxing LIU
1
;
Guohong ZHOU
;
Xiaodan ZHANG
Author Information
1. 山西医科大学第一临床医学院，太原 030001
- Keywords:
Myopia, degenerative;
Aqueous humor;
Proteins;
Cytokines;
Matrix metalloproteinase 2;
Fibrinolysin;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2022;38(9):784-788
- CountryChina
- Language:Chinese
-
Abstract:
The fundus lesions caused by high myopia (HM) often lead to irreversible visual impairment or even blindness. However, the pathogenesis of HM and its fundus lesions is still unclear, the intraocular fluid detection technology of micro samples has brought new prospects for the early diagnosis, monitoring and intervention of the fundus lesions. The molecules associated with HM are various and functionally diverse, intermolecular interactions are staggered and the specific mechanism is complex. With the development of intraocular fluid detection technology, while gradually revealing the role of each molecule in the pathogenesis of HM, it is expected to successfully assist clinical work in the future, providing outpost markers for the progress of myopia and targets for early intervention, or providing a new therapy choice for HM fundus lesions at the molecular level targeting pathogenesis, which is expected to provide more accurate and effective treatment for HM patients in the future.
