Research progress in clinical application of conversion surgery in stage cT4b esophageal cancer
10.3760/cma.j.cn112434-20210622-00209
- VernacularTitle:转化手术在cT4b期食管癌中的临床应用研究进展
- Author:
Kaiyuan JIANG
1
;
Dong TIAN
Author Information
1. 川北医学院附属医院胸外科，南充 637000
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2022;38(9):572-576
- CountryChina
- Language:Chinese
-
Abstract:
Because there is no serosal layer in the esophagus, cT4b stage esophageal cancer is prone to invade trachea, lung, aorta and other important organs with tumor metastasis, and the overall prognosis is very poor. The clinical results of radical chemotherapy or radiotherapy for these patients with advanced unresectable esophageal cancer are not ideal. In recent years, with the proposal of conversion surgery, patients with advanced unresectable esophageal cancer, surgical resection should be performed after the tumor-lowering stage and achieved through induction therapy. Some studies have reported its effectiveness and feasibility. However, there are different studies and reports on induction therapy regimens and postoperative survival rates. This paper reviews the development, induction therapy methods, surgical efficacy and prognosis of conversion surgery, aiming to summarize the clinical application of conversion surgery in recent years. To provide a theoretical basis for further formulation of the treatment strategy of this mode.
