A Case of Pyoderma Gangrenosum Treated with Clofazimine.
- Author:
Jun Young LEE
;
Sung Bum KANG
;
Baik Kee CHO
;
Won HOUH
- Publication Type:Case Report
- Keywords:
Pyoderma gangrenosum;
Clofazimine
- MeSH:
Clofazimine*;
Diarrhea;
Granulation Tissue;
Humans;
Male;
Pyoderma Gangrenosum*;
Pyoderma*;
Skin;
Ulcer;
Young Adult
- From:Korean Journal of Dermatology
1987;25(2):294-298
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We present herein a case of pyodcrma gangrenosum, who showed good response to clofazimine therapy. The patient, 19-year-old male, had suffered from chronic diarrhea for 10 months before the rapidly spreading pustules and ulcers with undermined purple-to-red borders devkloped on his both lower and upper extremitics. Clofazimine was given orally in a dose of 100mg three times daily for 16 days, and tapered to 100 mg two times daily for the next 11 days. Clinical improvement was noted after 7 day's treatment and the almost all of the skin lesiors were replaced by granulation tissue with epithelizatiori or crust formation after 6 days treatment.