Efficacy and thoughts of endoscopic submucosal dissection for rectal neuroendocrine tumor
10.3760/cma.j.cn321463-20220329-00155
- VernacularTitle:内镜黏膜下剥离术治疗直肠神经内分泌瘤的疗效及思考
- Author:
Yudong GUO
1
;
Xiufen TANG
;
Zijuan QI
;
Yan ZHAO
Author Information
1. 黑龙江省医院消化病院消化一科，哈尔滨150000
- Keywords:
Neuroendocrine tumors;
Rectum;
Endosonography;
Pathology, clinical;
Endoscopic submucosal dissection
- From:
Chinese Journal of Digestive Endoscopy
2022;39(7):564-567
- CountryChina
- Language:Chinese
-
Abstract:
To evaluate the efficacy and safety of endoscopic submucosal dissection (ESD) for rectal neuroendocrine tumor (RNET). Data of 71 patients (43 males and 28 females, aged 46.66±10.15 years) with histologically diagnosed RNET ≤15 mm in diameter who underwent ESD in Department One of Gastroenterology, Digestive Diseases Hospital, Heilongjiang Provincial Hospital from December 2012 to January 2021 were retrospectively analyzed. Epidemiological characteristics, endoscopic characteristics, the operation time, complications, pathology results, the consistency of endoscopic ultrasound (EUS) and pathology and prognosis were analyzed. Sixty-nine patients had single lesion and 2 patients had multiple lesions (two of each). Seventy lesions (70/73, 95.89%) were?located?in?the?middle-lower?rectal?segment, and 3 lesions (3/73, 4.11%) in the upper segment. The maximum diameter was 8.54±3.12 mm. The en bloc resection rate was 100%. No adverse event was observed. The R0 resection rate was 87.67% (64/73), with 8 had undetermined vertical resection margin and 1 had lymphovascular invasion. EUS showed no case involving the muscularis propria with pathologic coincidence rate of 100.0%. The follow-up period was 4.52±3.85 years (1-9 years). No local recurrence or distant metastasis was found. ESD is safe and effective in RNET ≤15 mm in diameter. For?tumors of G1 without metastasis in preoperative evaluation, close?follow-up?seems?to?be?a?feasible?option with lymphovascular invasion or undetermined margin after?ESD.
