Long-term outcomes of fully covered self-expanding metal stent for benign refractory pancreatic stenosis (with video)
10.3760/cma.j.cn321463-20210129-00772
- VernacularTitle:全覆膜自膨式金属支架治疗难治性胰管良性狭窄的长期疗效观察（含视频）
- Author:
Jun CAO
1
;
Yonghua SHEN
;
Ruhua ZHENG
;
Xiaoliang ZHOU
;
Zhengyan QIN
;
Lei WANG
;
Xiaoping ZOU
Author Information
1. 南京大学医学院附属鼓楼医院消化内科，南京 210008
- Keywords:
Pancreatitis, chronic;
Benign refractory pancreatic stenosis;
Fully covered self-expanding metal stent;
Long-term outcomes
- From:
Chinese Journal of Digestive Endoscopy
2022;39(6):447-452
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the safety and long-term outcomes of fully covered self-expanding metal stent (FCSEMS) placement in patients with benign refractory pancreatic stenosis.Methods:Data of 18 patients with benign refractory pancreatic stenosis who underwent endoscopic treatment with FCSEMS in Nanjing Drum Tower Hospital between March 2013 and July 2020 were collected. The technical success, clinical success, adverse events and long-term outcomes were analyzed.Results:FCSEMS placement was successful in all 18 patients, with technical success rate of 100.0% (18/18). After stenting, the visual analogue scale (VAS) significantly decreased [2.00 (1.75, 3.00) VS 6.00 (5.00, 7.00), Z=-3.572, P<0.001]. The VAS decreased by more than 50% in 15 cases, and the clinical success rate was 83.3% (15/18). Stent-related adverse events included intolerable pain in 3 patients, stented-induced de novo stricture in 2 patients, and distal migration of stent in 2 patients. The stents were successfully removed in all patients after 137.5 (59.0, 417.0) days. There was significant reduction in terms of decreased upstream ductal dilatation after stent removal [9.1 (6.7, 14.1) mm VS 11.0 (7.6, 16.2) mm, Z=10.508, P<0.001]. After stent removal, 10 of the 14 patients maintained the response to pancreatic stenting and 4 recurred during the follow-up of 37-1 246 days. Conclusion:FCSEMS placement appears to be safe and effective in the treatment of benign refractory pancreatic stenosis and can provide persistent improvement in the stricture.
