Progress in microRNA/lncRNA regulating dendritic cell differentiation, maturation and function
10.3760/cma.j.cn112309-20210920-00309
- VernacularTitle:microRNA/lncRNA调控树突状细胞分化、成熟及功能的研究进展
- Author:
Shanshan CAI
1
;
Jinyao LI
;
Lin YANG
;
Aipire ADILA·
Author Information
1. 新疆大学生命科学与技术学院，新疆生物资源基因工程重点实验室，乌鲁木齐 830046
- Keywords:
Dendritic cell;
Maturation;
Differentiation;
Function;
miRNA;
lncRNA
- From:
Chinese Journal of Microbiology and Immunology
2022;42(7):570-576
- CountryChina
- Language:Chinese
-
Abstract:
Dendritic cells (DC) as professional antigen-presenting cells can activate na?ve T cells and play an important role in bridging innate immunity and acquired immunity. Therefore, the differentiation and maturation of DC and the mechanism in its function regulatory have attracted much attention. With the rapid development of high-throughput sequencing, noncoding RNAs (ncRNAs) have been gradually known. In recent years, increasing studies have reported that ncRNAs play an importantly role in regulating the differentiation and maturation of DC. In this paper, the regulatory effects of microRNAs and long ncRNAs on the differentiation, maturation and function of DC were reviewed.
