Prognostic Value of Parent Arterial Lesions in the Patients with Lacunar Syndrome.
- Author:
Sung Yeol JOO
1
;
Se Ho OH
;
Jae Hyuk LEE
;
Kwang Gi HUH
;
Oh Young BANG
;
Kyoon HUH
Author Information
1. Department of Neurology, College of Medicine, Ajou University, Korea. nmboy@unitel.co.kr
- Publication Type:Original Article
- Keywords:
Infarction/Lacunar;
Prognosis;
Recurrence
- MeSH:
Arteries;
Embolism;
Humans;
Parents*;
Prognosis;
Recurrence;
Stroke;
Stroke, Lacunar*
- From:Journal of the Korean Neurological Association
2003;21(4):339-345
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: It is well known that a lacunar infarction has characteristic clinical features and a relatively good prognosis. However, the significance of lesions in the parent artery of patients with lacunar syndrome as regard to the prognosis remains unsettled. METHODS: Using the data of consecutive patients with their first ischemic stroke and were followed longer than 1 year, were divided the patients by their clinical features and the results of the work-up was as follows; (1) mismatching [MM] group; lacunar syndrome and the presence of parent arterial lesion, (2) large artery artherosclerosis [LAD]; non-lacunar syndrome and the presence of parent arterial lesion, (3) no determined etiology [NE]; non-lacunar syndrome without parent arterial lesion, and (4) small artery disease [SAD]; lacunar syndrome without parent arterial lesion. Patients with a potential source of embolism were excluded from this study. The prognosis and recurrence rate of patients with the MM group were compared with those of other groups. RESULTS: A total of 176 patients were included; 56 LAD, 62 SAD, 22 MM and 36 NE groups. An unstable hospital course was more frequently found in LAD than in the other groups. The recurrence rate of the MM group (23%) was significantly higher than that of SAD (2%), but was similar to that of patients with non-lacunar syndrome (LAD 16%, NE 28%). CONCLUSIONS: Among patients with lacunar syndrome, the prognosis of those with parent arterial lesions was different from those without lesions. Therefore, a systematic work up of the stroke mechanism may be important in patients with lacunar syndrome.
