Magnetic resonance imaging of children with cerebral palsy and their clinical characteristics
10.3760/cma.j.issn.0254-1424.2022.09.008
- VernacularTitle:脑性瘫痪儿童头颅MRI表现与其临床特点分析
- Author:
Jun WANG
1
;
Lijie ZHOU
;
Qianyu GUO
;
Bingbing LI
;
Chunya SU
;
Junying YUAN
;
Dengna ZHU
;
Huachun XIONG
;
Juan SONG
;
Yangyang CAO
Author Information
1. 郑州大学第三附属医院、河南省儿科疾病临床医学研究中心，郑州 450052
- Keywords:
Cerebral palsy;
Magnetic resonance imaging;
Clinical features;
Children;
Correlation analysis
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2022;44(9):800-804
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To document the clinical features of children with cerebral palsy (CP) using magnetic resonance imaging (MRI).Methods:The gross motor functioning of 325 children diagnosed as having CP was graded using the gross motor function classification system (GMFCS). The GMFCS grades were correlated with MRI results in univariate and multivariate logistic regression analyses. The significance of any relationship between the MRI results and co-morbidities was tested using chi-squared tests.Results:Cerebral dysplasia, cerebroventricular enlargement, periventricular leukomalacia (PVL), abnormal signals in the thalami, and morphological changes after hypoxic ischemic encephalopathy were all found to be significantly correlated with GMFCS grading. Moreover, the chi-squared tests indicated that PVL children, children with thinning of the corpus callosum and/or abnormal signals in the thalami were significantly more likely to have visual, auditory or speech impairment complications and/or mental retardation.Conclusions:The findings from MRI correlate well with types of CP, GMFCS grades and co-morbidities among CP children. MRI can be an effective tool for early diagnosis and prognosis of CP in children, indicating needs for clinical rehabilitation.
