Advances in drug prophylaxis against bronchopulmonary dysplasia

VernacularTitle:支气管肺发育不良的药物预防研究进展
Author: Xinghe BU ¹ ; Jianguo ZHOU
Author Information

1. 复旦大学附属儿科医院新生儿科，上海　201102
Keywords: Bronchopulmonary dysplasia; Drug therapy; Chemoprevention; Infant, premature
From: Chinese Journal of Perinatal Medicine 2022;25(9):703-708
CountryChina
Language:Chinese
Abstract: Bronchopulmonary dysplasia (BPD) is a common respiratory complication after preterm birth that severely affects the prognosis and quality of life in preterm infants. In recent years, significant progress has been made in neonatal care, but the incidence of BPD remains high. After long-term exploration and application, some medications such as exogenous pulmonary surfactants, glucocorticoids and caffeine have been widely used for the prevention and treatment of BPD. However, some medications including diuretics, inhaled nitric oxide and bronchodilators have not been proved to be effective and safe. This review summarizes the present drugs for the prevention of BPD in publications.