A Case of Parkinsonism Caused by Acetone Intoxication.
- Author:
Imsuk SUNG
1
;
Oh Young KWON
;
Heeyoung KANG
;
Donghwan KIM
;
Youngsoo KIM
;
Ki Jong PARK
;
Nack Cheon CHOI
;
Byeong Hoon LIM
Author Information
1. Department of Neurology, Gyeongsang National University College of Medicine, Korea. oykwon@nongae.gsnu.ac.kr
- Publication Type:Case Report
- Keywords:
Parkinsonian disorders;
Acetone;
Basal ganglia
- MeSH:
Acetone*;
Basal Ganglia;
Brain;
Eating;
Gait;
Ganglion Cysts;
Humans;
Hypokinesia;
Levodopa;
Magnetic Resonance Imaging;
Parkinsonian Disorders*
- From:Journal of the Korean Neurological Association
2003;21(4):422-425
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A variety of toxins cause parkinsonism and the lesions are primarily in the pallidostriatum. It usually does not respond to levodopa. We experienced a patient whose parkinsonian features developed after accidental acetone ingestion. She had rigidity, bradykinesia, gait disturbance and her speech was sluggish. Brain MRI showed bilateral basal ganglionic lesions. She was treated with levodopa and her neurological symptoms improved. To our knowledge, there has not been any previous reports of acetone causing parkinsonism. Acetone may cause parkinsonism by damaging the basal ganglia.
