Advances of cognitive impairment in amyotrophic lateral sclerosis
10.3760/cma.j.cn113694-20220222-00127
- VernacularTitle:肌萎缩侧索硬化患者认知损害的研究进展
- Author:
Tianmi YANG
1
;
Huifang SHANG
Author Information
1. 四川大学华西医院神经内科，成都 610041
- Keywords:
Amyotrophic lateral sclerosis;
Cognition disorders;
Review
- From:
Chinese Journal of Neurology
2022;55(11):1311-1317
- CountryChina
- Language:Chinese
-
Abstract:
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor deficits. In recent years, cognitive impairment in ALS has been widely concerned, and the concept of ALS-frontotemporal dementia spectrum has been commonly recognized and well-established. With the development of neuropsychology, neuroimaging, neurophysiology, neuropathology and neurogenetics, advances have been made in the diagnosis and pathophysiological mechanism of cognitive impairment in ALS. The most recent advances of cognitive impairment in ALS were reviewed.
