Dysfunction of lymphatic system and early Parkinson′s disease
10.3760/cma.j.cn113694-20220307-00172
- VernacularTitle:胶质淋巴系统功能障碍与早期帕金森病研究进展
- Author:
Zhaoying DONG
1
;
Oumei CHENG
Author Information
1. 重庆医科大学附属第一医院神经内科，重庆 400016
- Keywords:
Lymphatic system;
Neuroglia;
Parkinson disease;
Perivascular space
- From:
Chinese Journal of Neurology
2022;55(11):1306-1310
- CountryChina
- Language:Chinese
-
Abstract:
Lymphatic system is the transportation way of cerebrospinal fluid and brain interstitial fluid exchange. And this system is a central nervous drainage system which plays an important role in drainaging and discharging of metabolic waste in the brain. The function of this system can be evaluated indirectly by the perivascular space on magnetic resonance imaging. Parkinson′s disease is a common neurodegenerative disorder. It may be helpful to control the progression of the disease if the changes of perivascular space can be dynamically observed in the early or even prodromal stage of the disease. This article reviews the relationship between lymphatic system disfunction and early stage of Parkinson′s disease.
