Focusing on new research and clinical management of gastrointestinal symptoms in Parkinson′s disease
10.3760/cma.j.cn113694-20220817-00624
- VernacularTitle:加强帕金森病消化道症状的管理和研究
- Author:
Chengjie MAO
1
;
Xiaoyu CHENG
;
Chunfeng LIU
Author Information
1. 苏州大学附属第二医院神经内科，苏州 215004
- Keywords:
Parkinson disease;
Gastrointestinal symptoms;
Disease management
- From:
Chinese Journal of Neurology
2022;55(11):1209-1214
- CountryChina
- Language:Chinese
-
Abstract:
Gastrointestinal symptoms are common nonmotor symptoms of Parkinson′s disease, which are related closely to occurrence and progress of Parkinson′s disease, as well as throughout its whole process. For example, constipation can be an important symptom in prodromal stage of Parkinson′s disease, and gastroparesis would weaken the effect of drug by interfering pharmacokinetics. However, insufficient attention has been paid to the gastrointestinal symptoms of Parkinson′s disease presently, and there are few effective treatments, which compromise the quality of patients′ life greatly. The intervention focus on gut-brain axis, microbiota and gastrointestinal barrier may play a positive role in improving gastrointestinal symptoms and delaying the process of Parkinson′s disease.
