Research progress on the mechanism of peripheral immunity in Parkinson′s disease
10.3760/cma.j.cn113694-20220523-00415
- VernacularTitle:帕金森病外周免疫机制研究进展
- Author:
Shuying LIU
1
;
Chan PIU
Author Information
1. 首都医科大学宣武医院神经内科 国家老年疾病临床医学研究中心 国家神经疾病医学中心，北京 100053
- Keywords:
Parkinson disease;
Inflammation;
Immunity;
Pathogenesis
- From:
Chinese Journal of Neurology
2022;55(10):1180-1184
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson′s disease (PD) is a common aging-related neurodegenerative disease of the central nervous system. Its pathogenesis is a series of pathophysiological changes under the interaction of genetic factors and environmental risk factors. Recent studies have shown that the pathophysiologic mechanisms outside the central nervous system, especially inflammation and immune response, may play an important role in the pathogenesis of Parkinson′s disease. This article aims to review the up-to-date research results of the peripheral origin of PD, and to discuss the interplay and activation of the peripheral inflammatory immune system in PD.
