Research progress of neutrophil extracellular traps in the pathogenesis of ischemic stroke
10.3760/cma.j.cn113694-20220303-00155
- VernacularTitle:中性粒细胞外陷阱在缺血性脑卒中中作用的研究进展
- Author:
Lulu ZHANG
1
;
Juean JIANG
;
Hui WANG
;
Qi FANG
Author Information
1. 苏州大学附属第一医院神经内科，苏州215000
- Keywords:
Blood platelets;
Granulocytes;
Stroke;
Brain ischemia;
Neutrophil extracellular traps
- From:
Chinese Journal of Neurology
2022;55(10):1169-1175
- CountryChina
- Language:Chinese
-
Abstract:
Ischemic stroke is one of the primary causes of death and disability worldwide. Neutrophils can release depolymerized chromatin and proteins to form neutrophil extracellular traps (NETs) and participate in intravascular thrombus formation. In recent years, NETs have received increasing attention in the study of acute ischemic stroke. The results indicate that NETs play an important role in the pathogenesis of acute ischemic stroke. This review presented recent advances in the study of NETs in acute ischemic stroke.
