Cryptococcus neoformans meningoencephalitis
10.3760/cma.j.cn113694-20220406-00271
- VernacularTitle:隐球菌性脑膜炎
- Author:
Furong WANG
1
;
Qiming LIANG
Author Information
1. 华中科技大学同济医学院附属同济医院神经内科，武汉 430030
- Keywords:
Cryptococcus;
Meningitis;
HIV;
Antifungal agents;
Intracranial pressure
- From:
Chinese Journal of Neurology
2022;55(8):886-892
- CountryChina
- Language:Chinese
-
Abstract:
Cryptococcal meningitis is a central nervous system infection caused by cryptococcal invasion of meninges and (or) brain parenchyma. It is characterized by severe intracranial hypertension and brain parenchyma damage. This opportunistic infection commonly occurs among HIV infected individuals, organ transplant recipients, and other immunosuppressive situations, and otherwise immunologically normal hosts. The global burden of human immunodeficiency virus/acquired immunodeficiency syndrome has declined over the years, but cryptococcal meningitis still has a high morbidity and mortality. The risk groups, clinical presentation, imaging characteristics, diagnostic criteria and therapeutic issues were reviewed in this article.
