Advances in the application of immunoadsorption in autoimmune encephalitis
10.3760/cma.j.cn113694-20211105-00781
- VernacularTitle:免疫吸附在自身免疫性脑炎的应用进展
- Author:
Jinjin QIN
1
;
Wang MIAO
;
Junfang TENG
Author Information
1. 郑州大学第一附属医院神经重症监护室，郑州 475200
- Keywords:
Immunosorbent techniques;
Antibodies;
Plasma exchange;
Autoimmune encephalitis;
Immunotherapy
- From:
Chinese Journal of Neurology
2022;55(7):764-769
- CountryChina
- Language:Chinese
-
Abstract:
Immunoadsorption can selectively remove pathogenic antibodies and has recently achieved good results in neuroimmune diseases. The type and titer of pathogenic antibodies play an important role in the clinical symptoms and severity of patients with autoimmune encephalitis. First-line immunotherapy for autoimmune encephalitis includes steroids, intravenous immunoglobulin, plasma exchange or immunoadsorption. Immunoadsorption selectively and rapidly eliminates autoantibodies and can be an effective therapeutic option as part of multimodal immunotherapy.
