Liver quality standards and donor scoring system for citizen organ donation after death
10.3760/cma.j.cn113855-20220711-00454
- VernacularTitle:公民身后器官捐献肝脏质量标准供者评分系统研究
- Author:
Rui HE
1
;
Yingbin HUANG
;
Ming HAN
;
Xiaoping WANG
;
Jian ZHOU
;
Xiaopeng YUAN
;
Yitao ZHENG
;
Gang CHEN
;
Yuan LIAO
;
Jingdong LI
;
Xiaofeng ZHU
;
Qiang TAI
;
Jiefu HUANG
;
Xingyuan JIAO
Author Information
1. 中山大学附属第一医院器官移植中心，广州 510080
- Keywords:
Liver transplantation;
Primary graft dysfunction;
Donor score;
Donor liver score;
Propensity score matching
- From:
Chinese Journal of General Surgery
2022;37(11):801-806
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish donor liver quality related risk factors for the loss of function of transplanted liver.Methods:The data of donors and recipients of liver transplantation at the Organ Donation and Transplantation Center of the First Affiliated Hospital of Sun Yat-sen University from Nov 2011 to Dec 2018 were analyzed retrospectively. Propensity score matching (PSM) was performed to evaluate and screen the data of donors and recipients, in order to balance the covariates.Results:Of the organ donation, there were 70 males and 20 females , aging (40.6±16.3) years. Of the liver transplantation recipients, there were 70 males and 20 females , aging (41.8±20.3) years. Liver dysfunction after transplantation was significantly correlated with the following variables: the donor's CPR time( t=0.429, P=0.000), 15-minute retention rate of indocyanine green ( χ2=67.151, P=0.000), liver function grading ( χ2=54.154, P=0.000), bullae fatty liver grading ( χ2=8.120, P=0.017), vesicular fatty liver grading ( χ2=16.000, P=0.001), ICU stay time ( χ2=14.900, P=0.001)and serum creatinine level ( χ2=44.685, P=0.000). The donor scoring system was established in our studying. For the 90 organ donation cases, the donated liver quality were classified into four levels,which were of good correspondence to the prognosis of the recipients. Conclusion:This donor scoring system and grading standards established by analyzing the high-risk factors of liver dysfunction after transplantation helps evaluate the quality of donor liver in China.
