Risk factors of early postoperative complications after intersphincteric resection for low rectal cancer and construction of a nomogram prediction model
10.3760/cma.j.cn113855-20220430-00291
- VernacularTitle:低位直肠癌经括约肌间切除术后早期并发症的危险因素分析及预测模型的构建
- Author:
Hengduo QI
1
;
Yang LIU
;
Zhenyu ZHANG
;
Zhi GUO
;
Guangshuai LIN
;
Xiaojun LI
Author Information
1. 延安大学医学院，延安 716000
- Keywords:
Rectal neoplasms;
Postoperative complications;
Proctectomy;
Risk factor;
Nomogram prediction model
- From:
Chinese Journal of General Surgery
2022;37(10):743-748
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To identify the risk factors for postoperative early complications of low rectal cancer treated with intersphincteric resection (ISR).Methods:The perioperative data of 82 patients with low rectal cancer undergoing ISR at the General Surgery Department of Shaanxi Provincial People's Hospital between Jan 2017 to Dec 2021 were retrospectively analyzed. Univariate, Logistic regression and multivariate analysis were used to analyze the risk factors for early complications after ISR, and a nomogram prediction model was drawn. Predictive models are validated.Results:There were 22 patients (27%) with complications. Univariate analysis showed that early complications were related to diabetes (0.021), serum albumin (<0.001), nutritional prognosis index (0.003), neoadjuvant chemoradiotherapy (<0.001), and operation time (<0.001). By multivariate analysis, diabetes ( OR=4.853, 95% CI: 1.059-22.241, P=0.042), low serum albumin ( OR=0.672, 95% CI: 0.468-0.966, P=0.032), neoadjuvant chemoradiotherapy ( OR=4.482, 95% CI: 1.117-17.979, P=0.034) and longer operation time ( OR=1.015, 95% CI: 1.001-1.029, P=0.037) were independent risk factors A nomogram prediction model was thus constructed, and the area under the curve of the nomogram prediction model was 0.888 (95% CI: 0.812-0.965). Conclusion:Diabetes mellitus, low serum albumin, neoadjuvant chemoradiotherapy, and longer operation time are independent risk factors of early postoperative complications for low rectal cancer undergoing ISR.
