Modified Glasgow score in prediction of the prognosis of intrahepatic cholangiocarcinoma patients after radical surgical resection
10.3760/cma.j.cn113855-20210828-00519
- VernacularTitle:改良型格拉斯哥评分在肝内胆管细胞癌根治性切除患者的预后判断中的价值
- Author:
Shugeng WU
1
;
Caide LU
;
Shuqi MAO
;
Yongfei HUA
;
Gaoqing WANG
Author Information
1. 宁波大学附属宁波市医疗中心李惠利医院肝胆胰外科，宁波 315100
- Keywords:
Cholangiocarcinoma;
Glasgow outcome scale;
Preoperative inflammatory index
- From:
Chinese Journal of General Surgery
2022;37(7):514-517
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the correlation between modified Glasgow prognostic score (mGPS) and prognosis of intrahepatic cholangiocarcinoma (ICC) patients after radical surgical resection.Methods:The clinical data of 126 patients with intrahepatic cholangiocarcinoma undergoing radical surgical resection at Ningbo Medical Centre Lihuili Hospital from Jan 2011 to Dec 2020 were retrospectively analyzed. The patients were scored according to the mGPS-related scoring standards, and the differences in tumor clinicopathological characteristics and prognosis were compared between patients with different score levels.Results:Firty-eight cases were included in group 0, 41 cases in group 1, and 27 cases in group 2. The 1- and 3-year survival rates in group 0 were 85.8% and 52.3%, the 1- and 3-year survival rates in group 1 were 73.2% and 23%, and the 1- and 3-year survival rates in group 2 were 73.3% and 0. The difference was statistically significant ( P<0.05). Univariate analysis showed that age, mGPS, CA19-9, tumor diameter, and tumor differentiation were related at the prognosis of ICC. Multivariate analysis showed that age, tumor differentiation, tumor diameter and mGPS were independent risk factors for the prognosis of ICC. Conclusion:mGPS is an independent risk factor affecting the prognosis of ICC patients.
