Clinical features and treatment in patients with renovascular hypertension caused by renal arterial fibromuscular dysplasia
10.3760/cma.j.cn113855-20211118-00670
- VernacularTitle:肾动脉纤维肌性发育不良致肾血管性高血压的诊断与治疗
- Author:
Zhiling MA
1
;
Zhibin ZHOU
;
Zhaohui HUA
;
Zhouyang JIAO
;
Peng XU
;
Hui CAO
;
Shirui LIU
;
Zhen LI
Author Information
1. 郑州大学第一附属医院腔内血管外科，郑州 450052
- Keywords:
Fibromuscular dysplasia;
Renal artery;
Hypertension;
Percutaneous transluminal angioplasty;
Drug-coated balloon
- From:
Chinese Journal of General Surgery
2022;37(6):447-451
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinical characteristics and treatment of patients with renovascular hypertension (RVH) caused by renal arterial fibromuscular dysplasia (FMD).Methods:Clinical data and treatment result of 38 patients with renal arterial FMD and RVH admitted to our hospital from Jan 2014 to Dec 2020 were reviewed.Results:A total of 38 patients were enrolled in this study. Renal artery CTA showed that 40 renal arteries were involved, among these 6 branches had multifocal stenosis, and 34 branches had focal stenosis. Thity-three patients received surgical treatment, of which 32 patients underwent percutaneous transluminal renal angioplasty (PTRA), and 1 patient with renal aneurysm underwent renal artery stent implantation combined with aneurysm coil embolization. Postoperative blood pressure was significantly lower than that before the operation [(129.79±17.63) mmHg vs. (178.52±28.63) mmHg, t=-11.42, P<0.001]. The mean follow-up time was 35.5 months. Renal artery restenosis occurred in 4 patients and underwent reintervention. Conclusion:For patients with renal arterial FMD and RVH, PTRA is safe and effective, especially for patients with focal lesions, with fair short and mid-term prognosis.
