Cutaneous immune-related adverse reactions induced by immune checkpoint inhibitors

VernacularTitle:免疫检查点抑制剂所致皮肤免疫相关不良反应的研究进展
Author: Meirong ZOU ¹ ; Sheng WANG
Author Information

1. 四川大学华西医院皮肤科，成都　610041
Keywords: Drug toxicity; CTLA-4 antigen; Programmed cell death 1 receptor; Skin manifestations; Immune checkpoint inhibitors
From: Chinese Journal of Dermatology 2022;55(11):1026-1030
CountryChina
Language:Chinese
Abstract: As a new type of anti-cancer drugs, immune checkpoint inhibitors have been widely used for the treatment of various tumors in recent years, but they have also caused a variety of immune-related adverse reactions, among which cutaneous adverse reactions are the most common. The onset of cutaneous adverse reactions is usually early, and most are mild, but some can also be life-threatening. This review summarizes recent advances in cutaneous immune-related adverse reactions induced by immune checkpoint inhibitors.