Fetal programming: research status and reversal of intergenerational obesity caused by maternal obesity
10.3760/cma.j.cn311282-20210827-00555
- VernacularTitle:胎儿编程：母体肥胖引起代际肥胖的研究现状及逆转途径
- Author:
Wenhao WU
1
;
Jin LI
Author Information
1. 山西医科大学第二医院，太原 030000
- Keywords:
Fetal programming;
Obesity;
Intergenerational epigenetics
- From:
Chinese Journal of Endocrinology and Metabolism
2022;38(10):913-918
- CountryChina
- Language:Chinese
-
Abstract:
Fetal programming refers to as the process that organ structures and related functions undergo programming at the embryo and fetus phase. Any stimulus and injuries during embryo and fetal development can lead to changes in multiple fetal organs. Among them, maternal obesity is an important factor. This work reviews the data from recent animal models and human regarding the effects of maternal obesity on fetal programming, with a particular focus on the mechanisms and reversal strategies.
