Refractory hyponatremia caused by acute intermittent porphyria
10.3760/cma.j.cn311282-20211103-00699
- VernacularTitle:急性间歇性卟啉病所致顽固性低钠血症的临诊应对
- Author:
Qingyang LI
1
;
Yi REN
;
Jingtian HOU
;
Yunfeng LIU
;
Yan WANG
;
Jing YANG
Author Information
1. 山西医科大学第一医院内分泌科，太原 030001
- Keywords:
Acute intermittent porphyria;
Hyponatremia;
Syndrome of inappropriate antidiuretic hormone;
Tolvaptan
- From:
Chinese Journal of Endocrinology and Metabolism
2022;38(9):815-818
- CountryChina
- Language:Chinese
-
Abstract:
Hyponatremia is common in the attack of acute intermittent porphyria(AIP), which can cause epilepsy, coma and other adverse events and endanger the life of patients. Carbohydrate loading therapy is applied to control the attack of AIP in the clinic. But the application of glucose can exacerbate hyponatremia. It is difficult for clinicians to effectively correct hyponatremia while treating AIP with glucose. We reported a case of AIP whose refractory hyponatremia was corrected with short-term low-dose tolvaptan to improve knowledge in management.
