Adjuvant or salvage radiotherapy in patients with adverse pathological features after radical prostatectomy
10.3760/cma.j.cn112330-20211116-00594
- VernacularTitle:根治性前列腺切除术后不良病理特征患者的放疗选择
- Author:
Junliang ZHAO
1
;
Diwei ZHAO
;
Yang LIU
;
Liru HE
;
Fangjian ZHOU
;
Yonghong LI
Author Information
1. 中山大学肿瘤防治中心泌尿外科 华南肿瘤学国家重点实验室 肿瘤医学协同创新中心，广州 510060
- Keywords:
Prostatic neoplasms;
Carcinoma;
Radical prostatectomy;
Adverse pathological features;
Adjuvant radiotherapy;
Salvage radiotherapy
- From:
Chinese Journal of Urology
2022;43(7):555-558
- CountryChina
- Language:Chinese
-
Abstract:
Radical prostatectomy(RP)was commonly used in localized prostate cancer. For patients with adverse pathological features (APF) after RP, it was controversial about choosing adjuvant radiotherapy or salvage radiotherapy (SRT). Recent studies have found that early salvage radiotherapy(ESRT) had both the same cancer control and reduced overtreatment compared to adjuvant radiotherapy. Nomogram and Gene Classifier(GC) could predict the risk of recurrence after RP and contribute to choose adjuvant radiotherapy or ESRT. PSMA PET/CT was more sensitive to detect distant metastasis after biochemical recurrence, which was helpful to decide whether to implement SRT.
