Advances in the comprehensive treatment of muscle-invasive bladder cancer with preservation of the bladder
10.3760/cma.j.cn112330-20220314-00116
- VernacularTitle:肌层浸润性膀胱癌保留膀胱综合治疗的研究进展
- Author:
Zhiyong TAN
1
;
Shi FU
;
Ting LUAN
;
Yinglong HUANG
;
Haifeng WANG
;
Mingxia DING
;
Yigang ZUO
;
Jiansong WANG
Author Information
1. 昆明医科大学第二附属医院泌尿外科，昆明 650101
- Keywords:
Urinary bladder neoplasms;
Muscle invasive bladder cancer;
Bladder preservation;
Comprehensive treatment
- From:
Chinese Journal of Urology
2022;43(6):464-468
- CountryChina
- Language:Chinese
-
Abstract:
Bladder cancer(BC) ranks the first of genitourinary tumor in China and is one of the most common urological malignancies, in which 25%-30% of patients were diagnosed with muscle-invasive bladder cancer. Radical cystectomy combined with pelvic lymph node dissection is the standard procedure for treatment, which can effectively avoid tumor recurrence or distant metastasis as well as improve the prognosis of patients. However, some patients may not tolerate or refuse to undergo radical bladder surgery due to worry about high complication rate, high morbidity and poor postoperative quality of life. With the increasing understanding of bladder cancer heterogeneity and biological behavior, the treatment of bladder cancer has changed from a surgery-based treatment model to an individualized and comprehensive treatment model by multidisciplinary collaboration. The bladder-preserving treatment can achieve the same oncological prognosis as that of radical bladder surgery with a better quality of life of the patients, which has become a hot topic and focus of research in muscle-invasive bladder cancer treatment. This article reviewed the progress of research related to the comprehensive treatment of muscle-invasive bladder cancer with preservation of the bladder.
